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Exosome Research Direction
  • Tumor
  • Stem cell
  • Cardiovascular
  • Immunity
  • Nervous system
  • Methods and omics
  • Diagnosis
  • Targeted drug delivery
  • Secretory mechanism
Tumor
Tumor
Exosomes have a wide range of applications in tumor detection, tumor therapy and prognosis.
TumorRelated articles include10a piece of writing
Stem cells
Stem cell
Stem cell exosomes can be used as a novel cell therapy with a wide range of biological functions and medical applications.
Stem cellRelated articles include10a piece of writing
Cardiovascular
Cardiovascular
The therapeutic potential of exosomes for cell-free treatment of cardiovascular disease applies to a wide range of diseases, including myocardial infarction, atherosclerosis, and dilated cardiomyopathy.
CardiovascularRelated articles include9a piece of writing
Immunity
Immunity
Exosomes perform a variety of biological functions in the immune system.
ImmunityRelated articles include8a piece of writing
Nervous system
Nervous system
Exosomes can cross the blood-brain barrier, and have great potential for use in many neurological disorders and other areas.
Nervous systemRelated articles include3a piece of writing
Methodology and omics
Methods and omics
iversification studies of exosomes from different sources.
Methods and omicsRelated articles include7a piece of writing
Diagnosis
Diagnosis
Exosomes offer a novel approach to disease diagnosis.
DiagnosisRelated articles include10a piece of writing
Targeted drug delivery
Targeted drug delivery
Exosomes can be engineered to confer excellent targeting properties.
Targeted drug deliveryRelated articles include10a piece of writing
Secretory mechanism
Secretory mechanism
Exosomes are a key mediator of intercellular communication and play an important role in a variety of physiological and pathological processes.
Secretory mechanismRelated articles include10a piece of writing
Global exosome company
  • Exosomics

    总部位于意大利锡耶纳,正在开发基于外泌体的早期癌症筛查和分子诊断测试。公司提供检测外泌体中 RNA 和 DNA 突变的试剂盒和参考标准。这些试剂盒用于癌症筛查和液体活检,适用于研究使用和临床诊断。与 Lonza 公司有战略合作伙伴关系。Exosomics在从复杂生物流体中分离和选择性富集肿瘤来源的细胞外囊泡(EV)/外泌体方面拥有长期的专业知识和独特的知识产权。使命是开发和商业化基于循环细胞外囊泡和外泌体的分析的新一代癌症筛查和液体活检的测试。公司为癌症筛查和液体活检提供广泛的专用试剂和试剂盒,适用于研究和临床诊断。渠道涵盖EV /外泌体样品流的所有步骤,从预分析方法到实物分析。Exosomics预创一个靠简单抽血就能进行癌症诊断和监测的世界,使医生能够为每位患者选择最佳治疗方案。
     

  • Mursla

    2019年3月,Pierre Arsène在英国成立了Mursla公司,致力于利用外泌体生物学提供下一代多组学液体活检解决方案。经过3年多的发展,Mursla目前拥有多名液体活检领域研究经验丰富的顾问和一支优秀的研发团队。

    在外泌体制备方面,Mursla开发了一种通过结合密度缓冲和尺寸排除色谱(SEC)从血浆中分离出外泌体的新方法,得到的外泌体中的脂蛋白颗粒污染最小。同时,可提取血液中不同的外泌体亚群。

    在外泌体分析方面,Mursla合成了一个名叫ExoPheno™的技术平台工具,该平台通过机器学习集成了干、湿实验室分析,可以检测、分析血液中组织特异性外泌体的多组学“货物”,用于各种生物医学应用。

  • Nanostics

    Nanostics是一家专注于开发及商业化新型和非侵入性诊断测试的公司,其开发的新型液体活检平台,核心技术是将高灵敏度的细胞外囊泡(EV)/外泌体检测平台——英国Apogee纳米流式分析仪与先进的机器学习算法相结合,通过简单的血液收集即可进行检测诊断疾病,适用于各种癌症和其他疾病。目前在诊断膀胱癌和前列腺癌领域的成功必将为其他疾病的诊断和筛查带来意义非凡的技术方向和实践平台。核心技术ClarityDX®技术可用于疾病预测。鉴定病变细胞/组织表达的生物标志物 ,确定是否需要治疗 ,预测治疗反应和耐药性 ,疾病分期 ,识别疾病复发。

  • INOVIQ

    INOVIQ公司汇集了一系列基于外泌体的产品,可用于癌症和其他严重疾病的早期检测、诊断、预后和监测。具体来说,EXO-NET®可以“快速、准确、高效地从任何液体活检样本中捕获并分离外泌体”。该技术可与现有的自动化检测系统兼容,非常适合大批量临床样本的检测。

Well-known Exosome Experts
  • James E. Rothman

    Born 1950, USA Yale University, New Haven

  • Randy W. Schekman

    Born 1948, USA University of California, Berkeley

  • Thomas C. Südhof

    Born 1955,Germany Stanford University, Palo Alto

  • Raghu Kalluri

    Professor, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center

  • Aikawa, Elena

    Professor of Medicine, Harvard Medical School

  • Xandra Breakefield

    Professor of Neurology, Harvard Medical School

  • David Lyden

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • María Yáñez-Mó

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • Olivier De Wever

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • Peter Kierulf

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

Exosome Related Informations
  • Global
  • National